Jianping Cao, Professor

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Date: 2021-06-09 Author: Source: State Key Laboratory of Radiation Medicine and Protection Hits: 10

Jianping Cao M.D, Ph.D., Professor

Tel: +86-512-65880037

Email: jpcao@suda.edu.cn

Addres: 199 Renai Road, Suzhou Industrial Park, Suzhou(215123), JiangsuProvince, China

The professor and deputy director of Radiation Medicine and Protection School, Medical College, Soochow University. The leader of Radiation Biology Center, Radiation Medicine and Protection School.

Graduated from Suzhou Medical College and got M.D in 1984. From 1995 to 2002, working as visiting researcher at Takasaki Radiation Research Establishment, National Institute of Radiological Science of Japan (NIRS), GSF-National Research Center for Environment & Health, Germany, and University of Utah, USA, respectively.

The discipline member of the State Council . The member of national nuclear and radiation emergency team, the China project leader of radiation oncology group in FNCA (Forum of Nuclear Cooperation in Asia), etc. Have published about 200 research papers both domestic and abroad.

Research fields: radiation biological dosimeter, organs damage and repair caused by radiation, radiation sensitivity of tumor.

Publications :

1. Jinming Cao, Li Zhong, Yang Feng, Kun Qian, Yuji Xiao, Gaoren Wang, Wenling Tu, Ling Yue, Qi Zhang, Hongying Yang, Yang Jiao, Wei Zhu, Jianping Cao*. Activated Beta-catenin signaling ameliorates radiation-induced skin injury by suppressing marvel D3 expression. Radiation Research. 2021;(195):2: 173-190.

2. Jinming Cao, Wei Zhu, Daojiang Yu, Lu Pan, Li Zhong, Yuji Xiao, Yiying Gao, Yang Jiao, Qi Zhang, Jiang Ji, Hongying Yang, Shuyu Zhange*, Jianping Cao*. The Involvement of SDF-1α/CXCR4 Axis in Radiation-Induced Acute Injury and Fibrosis of Skin. Radiat Res. 2019;(192):4: 410-421.

3. He Y, Xu W, Xiao Y, Pan L, Chen G, Tang Y, Zhou J, Wu J, Zhu W, Zhang S*, Cao J*. Overexpression of Peroxiredoxin 6 (PRDX6) Promotes the Aggressive Phenotypes of Esophageal Squamous Cell Carcinoma.J Cancer.2018;9(21):3939-3949.

4. Xue J, Zhu W, Song J, Jiao Y, Luo J, Yu C, Zhou J, Wu J, Chen M, Ding WQ, Cao J*,Zhang S*. Activation of PPARα by clofibrate sensitizes pancreatic cancer cells to radiation through the Wnt/β-catenin pathway. Oncogene. 2018;37(7):953-962.

5. Yu C, Jiao Y, Xue J, Zhang Q, Yang H, Xing L, Chen G, Wu J, Zhang S, Zhu W*, Cao J*. Metformin Sensitizes Non-small Cell Lung Cancer Cells to an Epigallocatechin-3-Gallate (EGCG) Treatment by Suppressing the Nrf2/HO-1 Signaling Pathway. Int J Biol Sci. 2017;13(12):1560-1569.

6. Xue J, Yu C, Sheng W, Zhu W, Luo J, Zhang Q, Yang H, Cao H, Wang W, Zhou J, Wu J, Cao P, Chen M, Ding WQ, Cao J*, Zhang S*. The Nrf2/GCH1/BH4 axis ameliorates radiation-induced skin injury by modulating the ROS cascade. J Invest Dermatol. 2017;137(10):2059–2068.

7. Liu W, Chen Q, Wu S, Xia X, Wu A, Cui F, Gu YP, Zhang X, Cao J*. Radioprotector WR-2721 and mitigating peptidoglycan synergistically promote mouse survival through the amelioration of intestinal and bone marrow damage. J Radiat Res. 2015;56(2):278-86.

8. Zhang S*, Wang W, Gu Q, Xue J, Cao H, Tang Y, Xu X, Cao J*, Zhou J, Wu J, Ding WQ. Protein and miRNA profiling of radiation-induced skin injury in rats: the protective role of peroxiredoxin-6 (PRDX-6) against ionizing radiation. Free Radical Biol & Med. 2014;69:96-107.

9. Luo J, Zhu W, Tang Y, Cao H, Zhou Y, Ji R, Zhou X, Lu Z, Yang H, Zhang S, Cao J*. Artemisinin derivative artesunate induces radiosensitivity in cervical cancer cells in vitro and in vivo. Radiat Oncol. 2014;9:84.

10. Chen Q, Xia X, Wu S, Wu A, Qi D, Liu W, Cui F, Jiao Y, Zhu W, Gu Y, Gao H, Zhang X*, Cao J*. Apoptosis, necrosis, and autophagy in mouse intestinal damage after 15-Gy whole body irradiation.Cell Biochem Funct. 2014, 32(8):647-656.

11. Gu Q, Feng T, Cao H, Tang Y, Ge X, Luo J, Xue J, Wu J, Yang H, Zhang S*, Cao J*. HIV-TAT mediated protein transduction of Cu/Zn-superoxide dismutase-1 (SOD1) protects skin cells from ionizing radiation. Radiation Oncology 2013, 8:253.

12. Zhou J, Zhang S, Xie, Liu P, Xie F, Wu J*, Cao J*, Ding WQ. Overexpression of DNA polymerase iota (Po/ι) in esophageal squamous cell carcinoma. Cancer Science. 103(8):1574-79, 2012.