Quansheng Zhou, Professor

Academic History:

B.S., Suchow University, Dept. of Biochemistry,

Ph.D., Suchow University, Jiangsu Institute of Hematology,

Post-Doc., The Blood Center of Northwestern Wisconsin,

Professor, Soochow University, China, 2019-present.

Research Interests:

Hematology, Cancer biology, Radiation medicine and protection, novel anti-cancer drug discovery

Research Experience and Accomplishments:

Quansheng Zhou received his MD and PhD at Suzhou Medical College and engaged in research in USA from 1993 to 2008 as an investigator at the Scripps Research Institute in U.S.A. Currently, he is a principle investigator, and distinguished professor at the Cyrus Tang Hematology Center, Soochow University. He focuses on studying the cancer stem/progenitor cells in tumor neovascularization, and novel anti-cancer drug discovery. He has published more than 80 research papers on journals including Nature series and Blood, and he has been awarded six patents for invention. He has been listed in International Professional Who’s Who.

Academic Awards and Honors:

1、International Who’s Who of professionals 1998

2、New York Academy of Sciences, active member, since 1998..

3、Outstanding Graduate Students Award, Suzhou Medical College, 1991.

4、Excellent Teacher Award, Suzhou Medical College, 1982.

5、Outstanding Medical Students Award, Suzhou Medical College, 1977

6、Third class prize, Progress in Science and Technology (certificate No. 92-3-239-02), awarded by the Committee of Progress in Science and Technology of the Ministry of Chinese Nuclear Industry, 1992.

7、Third class prize, Progress in Science and technology (certificate No. 3-31-2), awarded by the Government of Suzhou City, 1994.

8、Fourth class prize, Progress in Science and Technology (certificate No. 4-184-2), awarded by theCommittee of Progress in Science and Technology of Jiangsu Province, 1994.

Main Publications:

1、Bo Yang, Bin Zhang, Zhifei Cao, Xingdong Xu, Zihe Huo, Pan Zhang, Shufen Xiang, Zhe Zhao, Chunping Lv, Mei Meng, Gaochuan Zhang, Liang Dong, Shucheng sShi, Lan Yang & Quansheng Zhou*.The Lipogenic LXR-SREBF1 Signaling Pathway Controls Cancer Cell DNA Repair and Apoptosis and Is a Vulnerable Point of Malignant Tumors for Cancer Therapy. Cell Death Differ,2020 Mar 6.DOI: 10.1038/s41418-020-0514-3.

2、Zhang G, Yang P, Guo P, Miele L, Sarkar FH, Wang Z, Zhou Q*. Unraveling the mystery of cancer metabolism in the genesis of tumor-initiating cells and development of cancer. BBA Rev Cancer 2013; 1836:49-59.

3、Shang B, Pan Y, Zhang G, Tu J, Zhou Y, Yang P, Cao Z, Wei Q, Ding Y, Zhang J, Zhao Y, Zhou Q*. CT45A1 acts as a new proto-oncogene to trigger tumorigenesis and cancer metastasis. Cell Death Disease 2014,5:e1285. doi: 10.1038 /cddis. 2014.24

4、Zhou Q, Kapoor M, Guo M, Belani R, Xu X, Kiosses WB, Hanan M, Park C, Armour E, Do MH, Nangle LA, Schimmel P, Yang XL. multifunctionality. Nature: Struc Mol Biol 2010; 17:57-61.

5、Sajish M, Zhou Q, Kishi S, Valdez D, Kapoor M, Guo M, Kim S, Yang X, Schimmel P. Nuclear TrpRS links IFN-γ signaling to p53 activation. Nat Chem Biol 2012; 8:547-54.

6、Zhou Q, Zhao J, Wiedmer T, Sims PJ. Normal hemostasis but defective hematopoietic response to growth factors in mice deficient in phospholipid scramblase. Blood 2002; 99:4030-4038.

7、Zhou Q, Zhao J, Zhou A, Wiedmer T, Sims PJ. Transcriptional control of human plasma membrane phospholipis scramblase 1 gene is mediated by interferon-alpha. Blood 1999; 95:2593-2599.

8、Zhou Q, Sims PJ, Wiedmer T. Expression of proteins controlling transbilayer movement of plasma membrane phospholipids in the B-lymphocytes from a patient with Scott syndrome. Blood 1998; 92:1707-1712.

Contact:

Phone: 0512-65882116

Email: zhouqs@suda.edu.cn

Fax: 0512-65880929

Office: 703-3505, Suchow University

Publication in 2020

1、Bo Yang, Bin Zhang, Zhifei Cao, Xingdong Xu, Zihe Huo, Pan Zhang, Shufen Xiang, Zhe Zhao, Chunping Lv, Mei Meng, Gaochuan Zhang, Liang Dong, Shucheng sShi, Lan Yang & Quansheng Zhou*.The Lipogenic LXR-SREBF1 Signaling Pathway Controls Cancer Cell DNA Repair and Apoptosis and Is a Vulnerable Point of Malignant Tumors for Cancer Therapy. Cell Death Differ,2020 Mar 6.DOI: 10.1038/s41418-020-0514-3.

2、Shufen Xiang, Zhe Zhao, Tong Zhang, Bin Zhang, Mei Meng, Zhifei Cao, Quansheng Zhou*.Triptonide Effectively Suppresses Gastric Tumor Growth and Metastasis Through Inhibition of the Oncogenic Notch1 and NF-κB Signaling Pathways.Toxicol Appl Pharmacol.2020 Feb 1;388:114870. doi: 10.1016.