CURRENT POSITIONS:

Director, Institutes for Translational Medicine of Soochow University

Vice President, The First Affiliated Hospital of Soochow University

Vice President, The Third Affiliated Hospital of Soochow University

ACADEMIC HISTORY:

1977-1982, DVM., Shandong Agricultural University, China.

 1985-1988, M.Sc., Zoology, University of Alberta, Canada

 1988-1992, Ph.D., Immunology, University of Alberta, Canada.

HONORS AND AWARDS

2020  Distinguished Professor, University of Rome Tor Vergata;

2020  Professor Jaap de Graaff Award, Leiden University;

 2016Award for Excellence in Translational Stem Cell Research, Chinese Society of Cell Biology

MAIN PUBLICATIONS:（^#Co-first Author *Corresponding Author）

1、Du L, Lin L, Li Q, Liu K, Huang Y, Wang X, Cao K, Chen X, Cao W, Li F, Shao C, Wang Y*, Shi Y*. IGF-2 Preprograms Maturing Macrophages to Acquire Oxidative Phosphorylation-Dependent Anti-inflammatory Properties. Cell Metab. 2019 Jun 4;29(6):1363-1375.e8. doi: 10.1016/j.cmet.2019.01.006.

2、Shi Y*, Wang Y, Li Q, Liu K, Hou J, Shao C, Wang Y*. Immunoregulatory mechanisms of mesenchymal stem and stromal cells in inflammatory diseases. Nat Rev Nephrol. 2018 Aug;14(8):493-507. doi: 10.1038/s41581-018-0023-5

3、Shi Y, Du LM, Lin LY, Wang Y. Tumor associated mesenchymal stem/stromal cells: emerging therapeutic targets. Nat Rev Drug Discov. 2017 Jan;16(1):35-52. doi: 10.1038/nrd.2016.193.

4、Wang Y, Chen X, Cao W, Shi Y*. Plasticity of mesenchymal stem cells in immunomodulation: pathological and therapeutic implications.Nat Immunol. 2014 Nov;15(11):1009-16. doi: 10.1038/ni.3002.

5、Ren G, Zhao X, Wang Y, Zhang X, Chen X, Xu C, Yuan Z, Roberts A, Zhang L, Zheng B, Wen T, Han Y, Rabson A, Tischfield J, Shao C, Shi Y*. CCR2-dependent recruitment of macrophages by tumor-educated mesenchymal stromal cells promotes tumor development and is mimicked by TNFα. Cell Stem Cell. 2012 Dec 7;11(6):812-24. doi: 10.1016/j.stem.2012.08.013.

6、Ren GW, Zhang LY, Zhao X, Xu GW, Zhang YY, Roberts AI, Zhao RC, Shi Y*. Mesenchymal Stem Cell-Mediated Immunosuppression Occurs via Concerted Action of Chemokines and Nitric Oxide.Cell Stem Cell. 2008 Feb 7;2(2):141-50. doi: 10.1016/j.stem.2007.11.014.

7、Devadas S, Das J, Liu C, Zhang L, Roberts AI, Pan Z, Moore PA, Das G, Shi Y*. Granzyme B is critical for T cell receptor-induced cell death of Type 2 helper T cells. Immunity. 2006 Aug;25(2):237-47. doi: 10.1016/j.immuni.2006.06.011.

8、Yin D, Mufson RA, Wang R, Shi Y*. Fas-mediated cell death promoted by opioids. Nature. 1999 Jan 21;397(6716):218.doi: 10.1038/16612

9、Shi Y, Glynn JM, Guilbert LJ, Cotter TG, Bissonnette RP and Green DR. Role for c-myc in activation-induced apoptotic cell death in T cell hybridomas. Science. 1992 Jul 10;257(5067):212-4. doi: 10.1126/science.1378649 (with cover illustration).

10、Shi Y, Sahai BM and Green DR. Cyclosporin A inhibits activation-induced cell death in T-cell hybridomas and thymocytes. Nature. 1989 Jun 22;339(6226):625-6. doi: 10.1038/339625a0.

CONTACT:

Phone: +86-13681668030

Email: yufangshi2@gmail.com